David Brooks claimed both goals as Bournemouth returned to winning ways by beating 10-man Brighton 2-0.
Wales international Brooks fired in from outside the box for the first-half opener, before heading home a second 13 minutes from time.
Albion were a man down for the final 17 minutes after captain Lewis Dunk was dismissed for two bookable offences.
The victory was just Bournemouth’s second from eight Premier League fixtures and inflicted a third successive loss on the visitors.
It also owed a lot to goalkeeper Asmir Begovic, who produced a string of fine first-half saves to deny Albion, keeping out efforts from Bissouma, Jurgen Locadia and Dunk.
Albion, on the back of defeats to Burnley and Chelsea, made the brighter start and almost edged in front when Bissouma was denied from close by Begovic following a one-two with Pascal Gross.
Seagulls left-back Bernardo then had to be alert to deny Junior Stanislas a tap-in following Callum Wilson’s cross-shot, before Begovic turned Locadia’s low shot from the edge of the D around the right post.
Brooks, one of three players recalled by Eddie Howe after last week’s loss at Wolves, opened the scoring in the 21st minute, calmly finding the bottom right corner after working space outside Brighton’s 18-yard area.
Jefferson Lerma collected his eighth booking of the season after cynically barging over Andone as the Brighton man broke threateningly from a Bournemouth corner, while Begovic did well to keep out a Dunk header.
The home side improved after the break and Stanislas almost doubled their advantage with a free-kick which whistled past the right upright after a foul on Brooks.
Television replays suggested Bissouma committed the foul which led to the set-piece, although referee Mike Dean booked Dunk.
It was Brighton’s third red card in seven games and their hopes of a fightback were effectively ended four minutes later as Brooks grabbed his second.
Cherries substitute Ryan Fraser produced an inswinging cross from the left and former Sheffield United midfielder Brooks rose to loop a header over Seagulls goalkeeper Mat Ryan.